Plus: Meet the dream engineers
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Hi readers,

 

How are you doing at sticking to any New Year’s resolutions you made? One of mine was to get off my tube train one stop early whenever I work in the office, to build more exercise into my day.

 

Sadly, I haven’t been keeping to this goal lately, but a study out this week in The BMJ has given me an extra incentive by adding to the growing evidence that exercise can improve our mental health, as well as our physical health.

 

The study was an analysis of 218 previous trials that looked at a range of treatments for depression. They included SSRI antidepressants, talking therapies and a variety of exercise programmes, such as walking, aerobic activities and strength training. All these strategies were effective, suggesting that doctors should consider exercise programmes alongside counselling or medication as three valid options to offer for depression, the authors say.

 

The analysis also came up with estimates for how effective each approach is, and generally some form of exercise or talking therapy seemed to give better results than taking medication, something that got wide media coverage this week.

 

I think we should be cautious about that part of the analysis, because few of the 218 trials compared the different approaches head to head, which would have been the best way to find out which is most effective. Most trialsjust compared the effectiveness of each strategy to a control group. But it does at least suggest that exercise programmes and talking therapies shouldn’t be seen as inferior to antidepressants.

 

Having this third strategy could be really helpful because some people don’t like the idea of taking medication. While effective for some, antidepressants can have side effects, such as agitation or making people feel as if their emotions are numbed, although some feel the latter is actually a benefit. The drugs can also be hard to stop taking, as I explore here. Last year, I wrote this feature-length article on how antidepressants work and what the prospects are for new treatments.

 

It is already recommended that talking therapy is given equal consideration to antidepressants, but there can be barriers to access, such as cost or long waiting lists. Exercise programmes have the advantage that most people could begin them immediately and at no or very little cost.

 

There is one big caveat, though. One of the most common symptoms of depression is “anhedonia”, when people find it hard to motivate themselves to do anything. If someone has severe anhedonia, such that they have difficulty even getting out of bed some days, they will undoubtedly also struggle to go for a run.

 

That aside, an important question is what kind of exercise programmes work best for depression. The BMJ analysis attempts to answer this question by ranking the different interventions by their effect size. Perhaps surprisingly, yoga was one of the most effective, a close second to walking or jogging.

Two people walk on a beach

Regular walks - as I'm enjoying here - can improve mood

But I still feel we should be sceptical of this kind of analysis for the reason I mentioned earlier – that most of the trials weren’tdirect comparisons of different approaches. To me, the key takeaway is that a wide variety of exercise strategies have the potential to help. And if motivation is a problem, it would make sense to pick the activity that is most personally appealing.

 

Unfortunately, whatever kind of treatment is tried – exercise, counselling or antidepressants – not everyone improves. If the first strategy tried doesn’t work, doctors generally recommend trying the others in turn, but it would be really helpful if people could know in advance which kind of intervention is most likely to help.

 

Separate research recently posted online has investigated this by analysing results from a Swedish trial that compared online counselling to exercise at three different intensity levels, three times a week. People were asked to wear movement trackers, both before and during the interventions. This let the researchers classify the participants by the strength of their circadian rhythm – in other words, whether or not they fell into the usual pattern of being more active in the daytime and sleeping at night.

 

They found that those who had more of a reduction in their depression symptoms in response to the vigorous exercise had a more regular circadian activity pattern. And those who did better from the gentler exercise classes or the counselling had more variability in their daily patterns of activity.

 

As this analysis wasn’t part of the initial trial, but a bonus question investigated later, we need to be cautious about assuming these conclusions are correct. They are certainly intriguing, though, and suggest future research avenues.

 

In the meantime, where does that leave people who want help with their depression? In the UK, exercise programmes are already supposed to be considered, but in practice, few GPs see it as a valid option, Jonathan Roiser at University College London said in a statement. “What is needed is a cultural shift in the way we think about treating depression which emphasises the important role that physical activity can play,” he said.

 

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The long read: Dream engineers

DongQiu

You may have heard of lucid dreaming, experienced by a lucky few people, who can become aware of their dreams and learn to direct the action. But what if we could all control our sleeping world and use those unconscious hours to our advantage?

 

That is the aim of the dream engineers. By manipulating people’s dreams, they have been able to promote learning, boost creativity, improve the quality of sleep, banish nightmares and more. Now they are developing technologies that will allow us all to do this for ourselves at home. It sounds like a dream come true, but could there be a dark side?

 

That’s all for this week. If you know someone who might enjoy this newsletter, please forward it to them. 

New Scientist health reporter Clare Wilson

Clare Wilson

Health reporter, New Scientist

Email me at healthcheck@newscientist.com
Follow me @clarewilsonmed

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